Managing gestational trophoblastic neoplasm (GTN) and people living with HIV (PLWH)

Authors

  • Pieter Barnardt Stellenbosch University

Keywords:

Gestational trophoblastic neoplasm, HIV, People living with HIV

Abstract

The 2017 World Health Organization (WHO) global report on HIV/AIDS estimated that sub-Saharan Africa comprised 64% of the global HIV burden, with a current estimate of 19.4 million cases in Eastern and Southern Africa. Since the introduction of antiretroviral therapy (ART) there has been a 30–40% increase in the incidence of non-AIDS malignancies. Gestational trophoblastic disease comprises of a spectrum of pregnancy-related disorders with an overall cure rate of 90%. The response to treatment is generally favourable but the associated complications of HIV, comorbidities, poor performance status and extent of metastatic disease in gestational trophoblastic neoplasm patients receiving chemotherapy, compromises the outcome and survival.

Author Biography

  • Pieter Barnardt, Stellenbosch University
    Department of Imaging and Clinical Oncology, Stellenbosch University, South Africa

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Published

2019-03-25

Issue

Vol. 11 No. 1 (2019)

Section

Guidelines

License

South African Journal of Gynaecological Oncology (SAJGO) Copyright is held by South African Society of Gynaecologic Oncology (SASGO). Copyright of the articles is held by the authors. The work is licensed under a Creative Commons Attribution-Non-Commercial Works 4.0 South Africa License (CC BY NC). Material submitted for publication in the SAJGO is accepted provided it has not been published elsewhere. The SAJGO does not hold itself responsible for statements made by the authors. The opinions expressed in this publication are those of the authors. They do no purport to reflect the opinions or views of SASGO or its members.